John S Condeelis Selected Research

Epidermal Growth Factor (EGF)

10/2018	A novel neuregulin - jagged1 paracrine loop in breast cancer transendothelial migration.
1/2018	Pyk2 and FAK differentially regulate invadopodia formation and function in breast cancer cells.
1/2018	Myosin-IIA heavy chain phosphorylation on S1943 regulates tumor metastasis.
1/2016	3-D individual cell based computational modeling of tumor cell-macrophage paracrine signaling mediated by EGF and CSF-1 gradients.
1/2016	Validation of a device for the active manipulation of the tumor microenvironment during intravital imaging.
11/2015	PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena.
11/2014	Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration.
8/2013	Wiskott-Aldrich syndrome protein regulates leukocyte-dependent breast cancer metastasis.
7/2012	Reconstitution of in vivo macrophage-tumor cell pairing and streaming motility on one-dimensional micro-patterned substrates.
1/2010	Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors.

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John S Condeelis Research Topics

Disease

58	Neoplasms (Cancer) 01/2022 - 11/2002
38	Breast Neoplasms (Breast Cancer) 04/2022 - 11/2002
36	Neoplasm Metastasis (Metastasis) 04/2022 - 11/2002
18	Carcinoma (Carcinomatosis) 01/2021 - 11/2002
3	Adenocarcinoma 01/2019 - 11/2004
2	Lymphatic Metastasis 01/2020 - 04/2009
2	Carcinogenesis 08/2013 - 03/2007
1	Pancreatitis 01/2022
1	Cardiomyopathies (Cardiomyopathy) 01/2020
1	Leukemia 01/2020
1	Necrosis 01/2020
1	Cytokine Release Syndrome 01/2019
1	Papillary Carcinoma 10/2018
1	Ductal Carcinoma 10/2018
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 11/2017
1	Colorectal Neoplasms (Colorectal Cancer) 10/2016
1	Hypoxia (Hypoxemia) 01/2016
1	Breast Ductal Carcinoma 11/2014
1	Fibrosarcoma 08/2012

Drug/Important Bio-Agent (IBA)

20	Epidermal Growth Factor (EGF)IBA 10/2018 - 11/2004
15	Proteins (Proteins, Gene)FDA Link 01/2021 - 03/2007
15	Protein Isoforms (Isoforms)IBA 01/2017 - 11/2004
7	Macrophage Colony-Stimulating FactorIBA 10/2018 - 06/2005
7	Messenger RNA (mRNA)IBA 10/2018 - 12/2004
6	Biomarkers (Surrogate Marker)IBA 04/2022 - 01/2009
5	Actin Depolymerizing Factors (Cofilins)IBA 12/2019 - 05/2006
4	CollagenIBA 01/2021 - 06/2005
4	Actins (F Actin)IBA 01/2021 - 12/2004
3	Estrogen ReceptorsIBA 01/2022 - 08/2014
3	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020 - 11/2004
3	LigandsIBA 10/2018 - 12/2009
3	ErbB Receptors (EGF Receptor)IBA 10/2018 - 06/2005
3	Phosphotransferases (Kinase)IBA 04/2018 - 12/2009
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2015 - 08/2003
3	Microfilament Proteins (Actin Binding Proteins)IBA 01/2010 - 12/2007
3	Complementary DNA (cDNA)IBA 12/2004 - 11/2002
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 11/2021 - 01/2018
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 07/2013
2	Pharmaceutical PreparationsIBA 01/2020 - 11/2004
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 11/2017
2	Phenobarbital (Luminal)FDA Link 10/2018 - 08/2011
2	RNA (Ribonucleic Acid)IBA 10/2018 - 10/2016
2	CortactinIBA 04/2018 - 01/2018
2	Hormones (Hormone)IBA 04/2018 - 04/2009
2	Matrix Metalloproteinases (MMPs)IBA 04/2018 - 07/2014
2	Paclitaxel (Taxol)FDA LinkGeneric 11/2017 - 01/2017
2	rebastinibIBA 11/2017 - 01/2017
2	Coloring Agents (Dyes)IBA 12/2016 - 01/2014
2	Peptide Hydrolases (Proteases)FDA Link 11/2016 - 08/2006
2	Metalloproteases (Metalloproteinases)IBA 08/2013 - 08/2006
2	Myosins (Myosin)IBA 04/2013 - 08/2006
2	AntibodiesIBA 09/2012 - 08/2003
2	Phosphatidylinositols (Phosphatidylinositol)IBA 12/2009 - 09/2007
2	Chemotactic FactorsIBA 12/2007 - 07/2006
2	Green Fluorescent ProteinsIBA 12/2002 - 11/2002
1	Tamoxifen FDA LinkGeneric 04/2022
1	CeruletideIBA 01/2022
1	taxaneIBA 01/2022
1	TIE-2 Receptor (Receptor, TIE 2)IBA 11/2021
1	LaminsIBA 01/2021
1	Estrogen Receptor alphaIBA 01/2019
1	Keratin-14 (Keratin 14)IBA 10/2018
1	Keratin-8 (Keratin 8)IBA 10/2018
1	AmphiregulinIBA 10/2018
1	NeuregulinsIBA 10/2018
1	Notch ReceptorsIBA 10/2018
1	Jagged-1 ProteinIBA 10/2018
1	human ERBB2 proteinIBA 04/2018
1	Focal Adhesion Protein-Tyrosine KinasesIBA 01/2018
1	Nonmuscle Myosin Type IIAIBA 01/2018
1	Tyrosine (L-Tyrosine)FDA Link 01/2018
1	GTP Phosphohydrolases (GTPases)IBA 12/2017
1	AngiopoietinsIBA 11/2017
1	eribulin FDA Link 11/2017
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 11/2017
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2017
1	Tricarboxylic AcidsIBA 11/2016
1	Glucose (Dextrose)FDA LinkGeneric 11/2016
1	Monoclonal AntibodiesIBA 03/2016
1	CateninsIBA 07/2014
1	FilaminsIBA 07/2014
1	Indicators and Reagents (Reagents)IBA 07/2014
1	CytokinesIBA 01/2014
1	Fibronectins (Fibronectin)IBA 01/2014
1	Wiskott-Aldrich Syndrome ProteinIBA 08/2013
1	Biological ProductsIBA 10/2012
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2012
1	Oncogene Proteins (Oncogene Protein)IBA 01/2010
1	ParaffinIBA 04/2009
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 04/2008
1	Actin-Related Protein 2-3 Complex (Arp2 3 Complex)IBA 04/2007
1	Mitogen-Activated Protein KinasesIBA 03/2007
1	Amino Acids FDA Link 03/2007
1	ActomyosinIBA 08/2006
1	Macrophage Colony-Stimulating Factor Receptor (Receptor, Macrophage Colony Stimulating Factor)IBA 06/2005
1	ElementsIBA 03/2005

Therapy/Procedure

10	Drug Therapy (Chemotherapy) 01/2022 - 11/2004
9	Therapeutics 04/2022 - 03/2005
2	Adjuvant Chemotherapy 01/2022 - 10/2018
2	Neoadjuvant Therapy 01/2022 - 01/2017